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pan caspase inhibitor cas  (TargetMol)


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    TargetMol pan caspase inhibitor cas
    Pan Caspase Inhibitor Cas, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/pan caspase inhibitor cas/product/TargetMol
    Average 93 stars, based on 5 article reviews
    pan caspase inhibitor cas - by Bioz Stars, 2026-02
    93/100 stars

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    (A) U87 cells were treated with 50 µM of decursin for various periods of time (0, 0.5, 1, 3 and 4 h). The cell lysates were subjected to Western blot analysis for phospho-JNK, total-JNK, phospho-p38 and total p38. (B) U87 cells were treated with 50 or 100 µM of decursin for 24 h. The cell lysates were subjected to Western blot analysis for Bax and Bcl-2 (C), cleaved caspase-3, 7, 9, PARP-1 and β-actin. Values are mean±SD (n=3). * p<0.05 vs. control. ** p<0.01 vs. control.

    Journal: The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology

    Article Title: Decursin induces apoptosis in glioblastoma cells, but not in glial cells via a mitochondria-related caspase pathway

    doi: 10.4196/kjpp.2019.23.1.29

    Figure Lengend Snippet: (A) U87 cells were treated with 50 µM of decursin for various periods of time (0, 0.5, 1, 3 and 4 h). The cell lysates were subjected to Western blot analysis for phospho-JNK, total-JNK, phospho-p38 and total p38. (B) U87 cells were treated with 50 or 100 µM of decursin for 24 h. The cell lysates were subjected to Western blot analysis for Bax and Bcl-2 (C), cleaved caspase-3, 7, 9, PARP-1 and β-actin. Values are mean±SD (n=3). * p<0.05 vs. control. ** p<0.01 vs. control.

    Article Snippet: Caspase apoptosis dependency was analyzed using 50 μM of pan caspase inhibitor (Cas I), p38 inhibitor (SB203580) and JNK inhibitor (SP600125) which were acquired from Calbiochem (EMD Millipore, Darmstadt, Germany).

    Techniques: Western Blot, Control

    (A) U87 cells were pre-treated with 5 µM of SB203580 (p38 inhibitor) and SP600125 (JNK inhibitor) for 30 min prior to decursin treatment (50 µM). Cell viability was determined by the MTT assay. (B) U87 cells were pre-treated with 10 µM of pan caspase inhibitor (Cas I) for 30 min prior to decursin treatment (50 µM). Cell viability was determined by the MTT assay. Values are mean±SD (n=4). ** p<0.01 vs. control.

    Journal: The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology

    Article Title: Decursin induces apoptosis in glioblastoma cells, but not in glial cells via a mitochondria-related caspase pathway

    doi: 10.4196/kjpp.2019.23.1.29

    Figure Lengend Snippet: (A) U87 cells were pre-treated with 5 µM of SB203580 (p38 inhibitor) and SP600125 (JNK inhibitor) for 30 min prior to decursin treatment (50 µM). Cell viability was determined by the MTT assay. (B) U87 cells were pre-treated with 10 µM of pan caspase inhibitor (Cas I) for 30 min prior to decursin treatment (50 µM). Cell viability was determined by the MTT assay. Values are mean±SD (n=4). ** p<0.01 vs. control.

    Article Snippet: Caspase apoptosis dependency was analyzed using 50 μM of pan caspase inhibitor (Cas I), p38 inhibitor (SB203580) and JNK inhibitor (SP600125) which were acquired from Calbiochem (EMD Millipore, Darmstadt, Germany).

    Techniques: MTT Assay, Control